Nuance
Multi-label imaging without cross-talk
As biological imaging becomes more about studying complex systems rather than single events, Nuance multispectral imaging systems enable users to quantitate molecular markers even when they are co-localized in a single tissue section, producing clear and accurate images of each individual label on a multi-label tissue section. These systems also offer the powerful capability to unmix and remove auto fluorescence in Nuance fluorescence images, thereby dramatically increasing signal-to-noise and improving the accuracy of your results. Nuance systems deliver flow-cytometry-like data while preserving the morphological context down to the sub-cellular level.
There are three Nuance models:
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Bandwidth Flexibility
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20 and 40 nm
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20 and 40 nm
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20 mm
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Scientific-Grade CCD
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Cooled Sony ICX285
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Cooled Sony ICX285
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Cooled Sony ICX285
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Mount Required*
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1x C-mount
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1x C-mount
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1x C-mount
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Acquisition and Analysis Software
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Yes
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Yes
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Yes
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Applications
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Brightfield
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Yes
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Yes
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Fluorescence
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Yes
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Yes
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Yes
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NIR Fluorescence
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Yes
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Yes
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*An F-mount macro lens is available for macroscopic applications.
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Nuance systems can be mounted on any microscope with a standard C-mount and offer CRi’s patented multispectral imaging capability at the sub-cellular, cellular and tissue level. Nuance’s powerful combination of multispectral hardware and sophisticated data analysis can dramatically improve tissue-based imaging.